This one is for all the computer guys out there my credit card has now had to be cancelled twice in 3 months due to fraud. I am trying to eliminate the problem being from my end
If you've been done twice in three months there is a common denominator that is being missed. If I'm not mistaken the new card would have a different/new number, expiry date and CVV number which should cover you against a second fraud.
My best guesses are there is some nasty software on your PC, or you have a bad password on some of your accounts which can be easily compromised or a one of the stores you purchase from has been compromised.
My money is on your PC or passwords being the issue. First thing I'd do is backup the data on your PC and then have it completely rebuilt and then fully patched by a trustworthy person. If it is an older PC (hopefully not XP) I'd be inclined to replace it as it will probably be a better investment overall. While Macs are far from perfect from a security point of view, overall the level of risk you are exposed to is typically/significantly less than a Windows PC. This is particularly true if you have no control over who is using your machine, for example kids, you never really know what they download.
I run Trend Micro titanium and a full scan turns up no issues
Trend products while they are improving typically don't score well in finding viruses depending on the review/test you read.
I also ran microsoft security centre full scan also with clean results
This product is in a similar boat. Just because these two products don't detect something does not mean you are safe.
Webroot is the AV product that prefer, I'd suggest you download this as a trial and see if it finds something for you:
http://www.webroot.com/au/en/home/products/trialsIs there anything extra a computer store or i can do to be sure my computer is clean 
They could do an offline scan where they boot from some known good media running good AV software. IMHO though a rebuild is the best/only way to start, however nasty software can reside in the PC BIOS which can be impossible to detect and remove at this time.
I'd also suggest you change all of your passwords on all of the sites you use with your CC, make sure you don't reuse the same password across multiple sites.
I assembled recently some links to government websites that provide some good advice on how to stay safe online if you are interested:
http://www.ethisec.com.au/resources/scams-online-snail-mail-e-mail-or-telephone/HTH,
Jason
BTW, this top 25 worst passwords of 2013 are not good passwords, I hope none of them are yours?
123456
password
12345678
qwerty
abc123
123456789
111111
1234567
iloveyou
adobe123
123123
admin
1234567890
letmein
photoshop
1234
monkey
shadow
sunshine
12345
password1
princess
azerty
trustno1
000000
