My wife, Amy, does ALL the driving , literally. My eyesight is shot, so don't have a licence.
We have done two trips around Aust. (+30.000kms each) lots of remote desert trips, and even OTL. All done with a fully laden Cruiser and camper.
Amy is amazing, and incredibly capable. I am very lucky, and very proud of her.
Thing is, she would have never done it if she didn't have to, but as with anything, practice and doing it has meant she can.
G